Abstract

Photoacoustic computed tomography (PACT) is a non-invasive imaging modality with wide medical applications. Conventional PACT image reconstruction algorithms suffer from wavefront distortion caused by the heterogeneous speed of sound (SOS) in tissue, which leads to image degradation. Accounting for these effects improves image quality, but measuring the SOS distribution is experimentally expensive. An alternative approach is to perform joint reconstruction of the initial pressure image and SOS using only the PA signals. Existing joint reconstruction methods come with limitations: high computational cost, inability to directly recover SOS, and reliance on inaccurate simplifying assumptions. Implicit neural representation, or neural fields, is an emerging technique in computer vision to learn an efficient and continuous representation of physical fields with a coordinate-based neural network. In this work, we introduce NF-APACT, an efficient self-supervised framework utilizing neural fields to estimate the SOS in service of an accurate and robust multi-channel deconvolution. Our method removes SOS aberrations an order of magnitude faster and more accurately than existing methods. We demonstrate the success of our method on a novel numerical phantom as well as an experimentally collected phantom and in vivo data. Our code and numerical phantom are available at https://github.com/Lukeli0425/NF-APACT.

Figure 1. Illustration of the proposed method.

Figure 4. Numerical simulation demonstrates accuracy and computational efficiency.

Figure 5. Real-world results.

Citation

@article{li2024neural,
    title={Neural Fields for Adaptive Photoacoustic Computed Tomography},
    author={Li, Tianao and Cui, Manxiu and Ma, Cheng and Alexander, Emma},
    journal={arXiv preprint arXiv:2409.10876},
    year={2024}
}

Acknowledgements

We would like to thank Liujie Gu and Yan Luo for helping us with the numerical simulations.
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